DEA schedules O-DSMT. Your supplements just got sketchier.

Key points

• The DEA is temporarily classifying the synthetic opioid O-desmethyltramadol (O-DSMT) as a Schedule I drug, the most restrictive category.
• This action is based on a finding of "imminent hazard to the public safety" and is effective August 12, 2026.
• The DEA notes that O-DSMT has been found in products falsely marketed as dietary supplements, posing a risk to consumers.
• No specific companies or financial beneficiaries are named in the DEA's public filing.
• The temporary scheduling order will last for two years, during which the DEA can pursue permanent classification.

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